After an individual sustains a traumatic brain injury (TBI), family members are thrown into a whirlwind of different emotions and decisions about their loved one’s care. Grief or a sense of loss may be associated with the ambiguity of the situation and changes in the survivor. Spouses, partners, parents, siblings and children may suddenly experience role changes associated with becoming a caregiver for the TBI survivor. As such, they may experience an increased responsibility for providing physical, financial and emotional support at a level they are not used to providing (Backhaus & Ibarra, 2012). The present article will discuss stressors unique to caregivers of persons with TBI, phases of adjustment post injury, challenges that family members typically experience when providing care, and the importance of recognizing and managing stress.