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In an explosive and masterfully written investigative piece by Harriet Ryan, Lisa Girion and Scott Glover,  the Los Angeles Times reported this week that in most patients the duration of the analgesic effect for OxyContin does not last nearly as long as claimed, and that this discrepancy may bear a large part of the blame for the current epidemic of opioid-related overdoses and deaths.

http://www.thepoisonreview.com/2016/05/07/absolute-must-read-la-times-on-the-myth-of-oxycontins-12-hour-analgesic-effect/